What is the Difference Between Sudafed and Sudafed PE

The main difference between Sudafed and Sudafed PE is that Sudafed contains the active ingredient pseudoephedrine, while Sudafed PE contains phenylephrine.

Sudafed and Sudafed PE are both over-the-counter medications that help to treat nasal congestion and other symptoms associated with allergies and colds.

Key Areas Covered

1. What is Sudafed
      – Definition, Features 
2. What is Sudafed PE
      – Definition, Features 
3. Similarities Between Sudafed and Sudafed PE
      – Outline of common features
4. Difference Between Sudafed and Sudafed PE
      – Comparison of Key Differences

Key Terms

Sudafed, Sudafed PE

Difference Between Sudafed and Sudafed PE - Comparison Summary

What is Sudafed

Sudafed is a brand of over-the-counter medication used to relieve nasal congestion and other symptoms associated with allergies, colds, and sinusitis. It contains the active ingredient pseudoephedrine, which is a decongestant that works by narrowing the blood vessels in the nasal passages and reducing swelling and congestion. Pseudoephedrine is also a sympathomimetic drug, which means that it mimics the effects of the sympathetic nervous system, which is responsible for the ‘fight or flight’ response. It functions by stimulating the alpha-adrenergic receptors in the nasal passages.

Sudafed is available in several different forms, such as tablets, capsules, and nasal sprays. The dosage and frequency of use will depend on the specific product and the severity of the symptoms.

Sudafed works quickly to relieve the congestion, usually within 15- 30 minutes. This can be particularly helpful for people who are experiencing severe nasal congestion and having difficulty in breathing. However, Sudafed should not be used for more than seven consecutive days because prolonged use can lead to rebound congestion, which can be more severe than the original symptoms.

Compare Sudafed and Sudafed PE - What's the difference?

Sudafed also has side effects, especially for people who are sensitive to the drug or who take too much of it. Some of the most common side effects of Sudafed include nervousness, restlessness, insomnia, increased heart rate, and increased blood pressure. In rare cases, it might cause more serious side effects such as seizures, hallucinations, and severe allergic reactions. It is always best to consult your doctor before taking Sudafed, especially if you have underlying health conditions.

What is Sudafed PE

Sudafed PE is an over-the-counter medication that contains phenylephrine, which is a decongestant that works by constricting blood vessels in the nasal passages, thereby reducing swelling and inflammation. It is used for the relief of nasal congestion and other symptoms associated with colds and allergies.

Phenylephrine is a synthetic compound that is structurally similar to the neurotransmitter epinephrine, which is responsible for the fight-or-flight response in the body. When phenylephrine is ingested, it is absorbed into the bloodstream and transported to the nasal tissues, where it acts on alpha-adrenergic receptors.

Sudafed PE is available in several forms, such as tablets, caplets, and liquid capsules. It does not cause drowsiness, unlike many other decongestants that contain pseudoephedrine.

Sudafed PE also has some side effects. The most common side effects are headache, nervousness, and nausea. In rare cases, it also can cause high blood pressure, irregular heart rhythms, and seizures. The use of sudafed PE is not advised for people who have high blood pressure, heart disease, diabetes, thyroid problems, or glaucoma. It is always advised to consult your healthcare provider before taking Sudafed PE, especially if you have any medical conditions or if you are taking other medications.

Similarities Between Sudafed and Sudafed PE

  • Sudafed and Sudafed PE are both medications that can provide relief for nasal congestion and other symptoms associated with colds and allergies.
  • Both have side effects like nervousness and restlessness.

Difference Between Sudafed and Sudafed PE

Definition

Sudafed is a brand name for a decongestant medication that contains pseudoephedrine as the active ingredient, while Sudafed PE is a brand name for a decongestant medication that contains phenylephrine as the active ingredient.

Active Ingredient

Sudafed contains the active ingredient pseudoephedrine, while Sudafed PE contains phenylephrine.

Side Effects

Moreover, Sudafed can cause more side effects than Sudafed PE, especially when taken in high doses.

Effectiveness

Sudafed is generally considered to be more effective than sudafed PE for severe congestion.

Drowsiness

Sudafed may cause drowsiness due to its active ingredient, while Sudafed PE does not cause drowsiness.

Conclusion

Sudafed and Sudafed PE are both over-the-counter medications that help to treat nasal congestion and other symptoms of allergies and colds. The main difference between Sudafed and Sudafed PE is that Sudafed contains the active ingredient pseudoephedrine, while Sudafed PE contains phenylephrine.

Reference:

1. “Sudafed – Uses, Side Effects, and More.” WebMD.
2. “CHILDRENS SUDAFED PE NASAL DECONGESTANT- phenylephrine hydrochloride solution.” Daily Med.

Image Courtesy:

1. “Sudafed Pills” By ParentingPatch – Own work (CC BY-SA 3.0) via Commons Wikimedia

About the Author: Hasini A

Hasini is a graduate of Applied Science with a strong background in forestry, environmental science, chemistry, and management science. She is an amateur photographer with a keen interest in exploring the wonders of nature and science.

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